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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA CXCL2 GDSC1000 pan-cancer AAC 0.13 0.0006
mRNA FKBP14 GDSC1000 pan-cancer AAC 0.13 0.0006
mRNA RAET1G GDSC1000 pan-cancer AAC 0.13 0.0006
mRNA FICD GDSC1000 pan-cancer AAC -0.12 0.0006
mRNA RASA1 GDSC1000 pan-cancer AAC 0.12 0.0006
mRNA OXSM GDSC1000 pan-cancer AAC -0.12 0.0007
mRNA PPP2R1B GDSC1000 pan-cancer AAC 0.12 0.0007
mRNA PLAU GDSC1000 pan-cancer AAC 0.14 0.0007
mRNA NNMT GDSC1000 pan-cancer AAC 0.14 0.0007
mRNA TGFBI GDSC1000 pan-cancer AAC 0.14 0.0007
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