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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA AHR GDSC1000 pan-cancer AAC 0.064 0.09
mRNA SEC11C GDSC1000 pan-cancer AAC -0.063 0.09
mRNA IGF2 GDSC1000 pan-cancer AAC -0.06 0.09
mRNA HOXA7 GDSC1000 pan-cancer AAC -0.058 0.09
mRNA SH3BP1 GDSC1000 pan-cancer AAC -0.07 0.09
mRNA PIGM GDSC1000 pan-cancer AAC -0.059 0.09
mRNA OSBPL6 GDSC1000 pan-cancer AAC -0.06 0.09
mRNA NR2C2 GDSC1000 pan-cancer AAC -0.061 0.09
mRNA GBX2 GDSC1000 pan-cancer AAC -0.057 0.09
mRNA RNF216 GDSC1000 pan-cancer AAC 0.059 0.09
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