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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM155 GDSC1000 pan-cancer AAC 0.077 0.02
mRNA WDR31 GDSC1000 pan-cancer AAC -0.08 0.02
mRNA RETNLB GDSC1000 pan-cancer AAC -0.079 0.02
mRNA IL36RN GDSC1000 pan-cancer AAC 0.085 0.02
mRNA TEAD1 GDSC1000 pan-cancer AAC 0.089 0.02
mRNA TMEM8B GDSC1000 pan-cancer AAC -0.08 0.02
mRNA DHX57 GDSC1000 pan-cancer AAC -0.082 0.02
mRNA L1TD1 GDSC1000 pan-cancer AAC 0.079 0.02
mRNA ZNF615 GDSC1000 pan-cancer AAC -0.081 0.02
mRNA CDH22 GDSC1000 pan-cancer AAC -0.081 0.02
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