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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA TSPAN33 GDSC1000 pan-cancer AAC -0.097 0.01
mRNA PLCD1 GDSC1000 pan-cancer AAC -0.089 0.01
mRNA CXCL8 GDSC1000 pan-cancer AAC 0.093 0.01
mRNA DCBLD2 GDSC1000 pan-cancer AAC 0.11 0.01
mRNA PCYOX1L GDSC1000 pan-cancer AAC -0.093 0.01
mRNA NEDD4 GDSC1000 pan-cancer AAC 0.094 0.01
mRNA MPND GDSC1000 pan-cancer AAC -0.088 0.01
mRNA GLS2 GDSC1000 pan-cancer AAC -0.094 0.01
mRNA LRRC74A GDSC1000 pan-cancer AAC 0.087 0.01
mRNA IFNA7 GDSC1000 pan-cancer AAC 0.086 0.01
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