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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA KCNQ1 GDSC1000 pan-cancer AAC -0.14 0.0003
mRNA MCTP2 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA NUDT16 GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA COL16A1 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA GPX8 GDSC1000 pan-cancer AAC 0.17 0.0003
mRNA ZPBP2 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA LRRC17 GDSC1000 pan-cancer AAC 0.15 0.0004
mRNA HERPUD2 GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA ANXA3 GDSC1000 pan-cancer AAC 0.15 0.0004
mRNA GKN2 GDSC1000 pan-cancer AAC 0.12 0.0004
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