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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA TPD52L1 GDSC1000 pan-cancer AAC 0.081 0.07
mRNA NEUROG3 GDSC1000 pan-cancer AAC -0.059 0.08
mRNA CHCHD6 GDSC1000 pan-cancer AAC -0.068 0.08
mRNA SLC7A5 GDSC1000 pan-cancer AAC 0.064 0.08
mRNA ZNF674 GDSC1000 pan-cancer AAC -0.062 0.08
mRNA FZD7 GDSC1000 pan-cancer AAC 0.069 0.08
mRNA SLIT3 GDSC1000 pan-cancer AAC 0.069 0.08
mRNA PGLYRP3 GDSC1000 pan-cancer AAC 0.06 0.08
mRNA TCFL5 GDSC1000 pan-cancer AAC -0.061 0.08
mRNA DRD5 GDSC1000 pan-cancer AAC 0.059 0.08
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