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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA IFNGR1 GDSC1000 pan-cancer AAC 0.066 0.06
mRNA HPN GDSC1000 pan-cancer AAC -0.066 0.06
mRNA IRF1 GDSC1000 pan-cancer AAC 0.073 0.06
mRNA FLVCR1 GDSC1000 pan-cancer AAC -0.068 0.06
mRNA VAMP1 GDSC1000 pan-cancer AAC 0.07 0.06
mRNA MTHFR GDSC1000 pan-cancer AAC -0.066 0.06
mRNA RRAGC GDSC1000 pan-cancer AAC -0.064 0.06
mRNA NDUFAF3 GDSC1000 pan-cancer AAC -0.064 0.06
mRNA ATRAID GDSC1000 pan-cancer AAC -0.065 0.06
mRNA DIRAS2 GDSC1000 pan-cancer AAC -0.063 0.06
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