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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA COL4A5 GDSC1000 pan-cancer AAC 0.12 0.003
mRNA ARNTL2 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA DDX60L GDSC1000 pan-cancer AAC 0.11 0.003
mRNA MMP2 GDSC1000 pan-cancer AAC 0.12 0.003
mRNA TBC1D29 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA HADHA GDSC1000 pan-cancer AAC -0.11 0.003
mRNA CD69 GDSC1000 pan-cancer AAC 0.12 0.003
mRNA UNC119B GDSC1000 pan-cancer AAC -0.1 0.003
mRNA GGT7 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA SKIV2L2 GDSC1000 pan-cancer AAC 0.1 0.003
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