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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA THBS1 GDSC1000 pan-cancer AAC 0.14 0.0007
mRNA ACTR5 GDSC1000 pan-cancer AAC -0.12 0.0007
mRNA MYO1B GDSC1000 pan-cancer AAC 0.15 0.0008
mRNA PTPDC1 GDSC1000 pan-cancer AAC -0.12 0.0008
mRNA RBMS2 GDSC1000 pan-cancer AAC 0.13 0.0008
mRNA CYS1 GDSC1000 pan-cancer AAC -0.11 0.0008
mRNA CXCL1 GDSC1000 pan-cancer AAC 0.13 0.0008
mRNA EIF1B GDSC1000 pan-cancer AAC -0.13 0.0008
mRNA ITGAV GDSC1000 pan-cancer AAC 0.14 0.0009
mRNA COL4A1 GDSC1000 pan-cancer AAC 0.15 0.0009
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