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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA GALNT2 GDSC1000 pan-cancer AAC 0.084 0.02
mRNA BID GDSC1000 pan-cancer AAC 0.081 0.02
mRNA INPP4A GDSC1000 pan-cancer AAC -0.082 0.02
mRNA FSCB GDSC1000 pan-cancer AAC 0.078 0.02
mRNA GLRX GDSC1000 pan-cancer AAC 0.085 0.02
mRNA PHLDA1 GDSC1000 pan-cancer AAC 0.099 0.02
mRNA SLC22A24 GDSC1000 pan-cancer AAC -0.078 0.02
mRNA PCED1A GDSC1000 pan-cancer AAC -0.08 0.02
mRNA RAB3IL1 GDSC1000 pan-cancer AAC -0.081 0.02
mRNA SRSF6 GDSC1000 pan-cancer AAC -0.079 0.02
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