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XAV-939

XAV-939

Synonyms

Sources	Names Used
GDSC1000	XAV939
PharmacoGx	XAV-939

External IDs

Database	Identifier
Smiles:	C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey:	KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem:	2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XAV-939

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SVIL	GDSC1000	pan-cancer	AAC	0.09	0.02
mRNA	ZP4	GDSC1000	pan-cancer	AAC	0.076	0.02
mRNA	FAM118A	GDSC1000	pan-cancer	AAC	-0.083	0.02
mRNA	FRK	GDSC1000	pan-cancer	AAC	0.088	0.02
mRNA	PPBP	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	DPM3	GDSC1000	pan-cancer	AAC	-0.079	0.02
mRNA	HBEGF	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	TLR2	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	CLMP	GDSC1000	pan-cancer	AAC	0.088	0.02
mRNA	FAT2	GDSC1000	pan-cancer	AAC	0.099	0.02

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