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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA AHCYL2 GDSC1000 pan-cancer AAC -0.089 0.01
mRNA LAMC2 GDSC1000 pan-cancer AAC 0.11 0.01
mRNA NUP210 GDSC1000 pan-cancer AAC -0.12 0.01
mRNA PPP1R3C GDSC1000 pan-cancer AAC 0.097 0.01
mRNA PRR29 GDSC1000 pan-cancer AAC -0.086 0.01
mRNA RASSF1 GDSC1000 pan-cancer AAC -0.099 0.01
mRNA MOS GDSC1000 pan-cancer AAC -0.084 0.01
mRNA REL GDSC1000 pan-cancer AAC 0.099 0.01
mRNA PSMG3 GDSC1000 pan-cancer AAC 0.09 0.01
mRNA EBF4 GDSC1000 pan-cancer AAC -0.085 0.01
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