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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM133 GDSC1000 pan-cancer AAC 0.097 0.007
mRNA KLHL7 GDSC1000 pan-cancer AAC 0.095 0.007
mRNA RFNG GDSC1000 pan-cancer AAC -0.092 0.007
mRNA TNFRSF18 GDSC1000 pan-cancer AAC -0.091 0.007
mRNA IGFL1 GDSC1000 pan-cancer AAC 0.099 0.007
mRNA MMP28 GDSC1000 pan-cancer AAC 0.1 0.007
mRNA PLEKHA8 GDSC1000 pan-cancer AAC 0.092 0.007
mRNA ZNF880 GDSC1000 pan-cancer AAC -0.098 0.007
mRNA RAE1 GDSC1000 pan-cancer AAC -0.091 0.007
mRNA MYL5 GDSC1000 pan-cancer AAC -0.091 0.007
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