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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA WDR4 GDSC1000 pan-cancer AAC 0.097 0.004
mRNA VEGFC GDSC1000 pan-cancer AAC 0.12 0.004
mRNA IL18 GDSC1000 pan-cancer AAC 0.12 0.004
mRNA CTNND1 GDSC1000 pan-cancer AAC 0.12 0.004
mRNA NT5M GDSC1000 pan-cancer AAC -0.1 0.004
mRNA ZBED2 GDSC1000 pan-cancer AAC 0.11 0.004
mRNA FAM105A GDSC1000 pan-cancer AAC -0.1 0.004
mRNA AFAP1L2 GDSC1000 pan-cancer AAC 0.11 0.004
mRNA IL16 GDSC1000 pan-cancer AAC -0.14 0.005
mRNA NAPA GDSC1000 pan-cancer AAC -0.1 0.005
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