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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA RWDD2A GDSC1000 pan-cancer AAC -0.1 0.003
mRNA NCOA7 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA SLC38A9 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA LRSAM1 GDSC1000 pan-cancer AAC -0.099 0.003
mRNA RPS6KL1 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA NRP2 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA VPS11 GDSC1000 pan-cancer AAC -0.1 0.004
mRNA SMCO2 GDSC1000 pan-cancer AAC 0.1 0.004
mRNA SNX6 GDSC1000 pan-cancer AAC 0.11 0.004
mRNA XPR1 GDSC1000 pan-cancer AAC 0.11 0.004
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