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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA FGD6 GDSC1000 pan-cancer AAC 0.21 5e-08
mRNA TBL1XR1 GDSC1000 pan-cancer AAC -0.15 6e-06
mRNA C7orf72 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA PHLDB2 GDSC1000 pan-cancer AAC 0.18 1e-05
mRNA ZNF621 GDSC1000 pan-cancer AAC -0.14 3e-05
mRNA RAB40B GDSC1000 pan-cancer AAC -0.15 4e-05
mRNA TMEM52 GDSC1000 pan-cancer AAC -0.15 4e-05
mRNA PALLD GDSC1000 pan-cancer AAC 0.18 5e-05
mRNA CBX7 GDSC1000 pan-cancer AAC -0.14 6e-05
mRNA SLC25A38 GDSC1000 pan-cancer AAC -0.15 9e-05
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