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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA EDIL3 GDSC1000 pan-cancer AAC 0.1 0.006
mRNA PAPPA GDSC1000 pan-cancer AAC 0.11 0.006
mRNA RNF114 GDSC1000 pan-cancer AAC -0.097 0.006
mRNA PRKCZ GDSC1000 pan-cancer AAC -0.11 0.006
mRNA SPRR2E GDSC1000 pan-cancer AAC 0.096 0.006
mRNA PMM1 GDSC1000 pan-cancer AAC -0.097 0.006
mRNA PPARA GDSC1000 pan-cancer AAC -0.097 0.006
mRNA SLCO4A1 GDSC1000 pan-cancer AAC -0.1 0.006
mRNA CERS3 GDSC1000 pan-cancer AAC 0.11 0.006
mRNA CFH GDSC1000 pan-cancer AAC 0.095 0.006
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