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XAV-939

XAV-939

Synonyms

Sources	Names Used
GDSC1000	XAV939
PharmacoGx	XAV-939

External IDs

Database	Identifier
Smiles:	C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey:	KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem:	2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XAV-939

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GOT1	GDSC1000	pan-cancer	AAC	-0.058	0.09
mRNA	ADAMTS12	GDSC1000	pan-cancer	AAC	-0.062	0.09
mRNA	NEMP1	GDSC1000	pan-cancer	AAC	-0.064	0.09
mRNA	PTPN2	GDSC1000	pan-cancer	AAC	0.061	0.09
mRNA	DOK2	GDSC1000	pan-cancer	AAC	-0.065	0.09
mRNA	BRIP1	GDSC1000	pan-cancer	AAC	0.059	0.09
mRNA	FUBP1	GDSC1000	pan-cancer	AAC	0.059	0.09
mRNA	MRGPRX4	GDSC1000	pan-cancer	AAC	0.059	0.09
mRNA	KLF7	GDSC1000	pan-cancer	AAC	0.065	0.09
mRNA	TMEM115	GDSC1000	pan-cancer	AAC	-0.061	0.09

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