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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA FABP12 GDSC1000 pan-cancer AAC 0.057 0.09
mRNA POP5 GDSC1000 pan-cancer AAC -0.059 0.09
mRNA IRS1 GDSC1000 pan-cancer AAC 0.066 0.09
mRNA CFL2 GDSC1000 pan-cancer AAC 0.08 0.09
mRNA LRRC8A GDSC1000 pan-cancer AAC 0.07 0.09
mRNA PDE4C GDSC1000 pan-cancer AAC -0.058 0.09
mRNA RGL3 GDSC1000 pan-cancer AAC -0.063 0.09
mRNA KLHL36 GDSC1000 pan-cancer AAC 0.063 0.09
mRNA AVPI1 GDSC1000 pan-cancer AAC 0.073 0.09
mRNA ADAMTSL1 GDSC1000 pan-cancer AAC -0.059 0.09
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