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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA KLK15 GDSC1000 pan-cancer AAC -0.06 0.08
mRNA RAB29 GDSC1000 pan-cancer AAC -0.061 0.08
mRNA METTL21C GDSC1000 pan-cancer AAC 0.059 0.08
mRNA XYLB GDSC1000 pan-cancer AAC -0.069 0.08
mRNA LCN1 GDSC1000 pan-cancer AAC -0.059 0.08
mRNA COL4A3BP GDSC1000 pan-cancer AAC 0.063 0.08
mRNA THAP3 GDSC1000 pan-cancer AAC -0.062 0.08
mRNA PAX8 GDSC1000 pan-cancer AAC -0.08 0.08
mRNA ESM1 GDSC1000 pan-cancer AAC -0.06 0.08
mRNA TMEM55B GDSC1000 pan-cancer AAC -0.062 0.08
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