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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA FGR GDSC1000 pan-cancer AAC -0.072 0.06
mRNA KRT81 GDSC1000 pan-cancer AAC 0.067 0.06
mRNA THEM6 GDSC1000 pan-cancer AAC -0.068 0.06
mRNA WNT16 GDSC1000 pan-cancer AAC 0.061 0.06
mRNA SEPT3 GDSC1000 pan-cancer AAC -0.067 0.06
mRNA DRG1 GDSC1000 pan-cancer AAC -0.065 0.06
mRNA IGF1 GDSC1000 pan-cancer AAC -0.065 0.06
mRNA PPP1R1B GDSC1000 pan-cancer AAC -0.071 0.06
mRNA LRIT1 GDSC1000 pan-cancer AAC 0.062 0.06
mRNA TTC19 GDSC1000 pan-cancer AAC -0.062 0.06
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