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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA VAPB GDSC1000 pan-cancer AAC -0.087 0.02
mRNA PDK2 GDSC1000 pan-cancer AAC -0.081 0.02
mRNA ZNF528 GDSC1000 pan-cancer AAC -0.085 0.02
mRNA POLK GDSC1000 pan-cancer AAC 0.087 0.02
mRNA ACTB GDSC1000 pan-cancer AAC 0.083 0.02
mRNA TNRC6C GDSC1000 pan-cancer AAC -0.088 0.02
mRNA MMP27 GDSC1000 pan-cancer AAC 0.081 0.02
mRNA FAHD2B GDSC1000 pan-cancer AAC -0.084 0.02
mRNA CHD1 GDSC1000 pan-cancer AAC 0.085 0.02
mRNA BCKDK GDSC1000 pan-cancer AAC -0.084 0.02
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