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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA GID8 GDSC1000 pan-cancer AAC -0.097 0.007
mRNA ZMYM1 GDSC1000 pan-cancer AAC 0.099 0.007
mRNA ST3GAL6 GDSC1000 pan-cancer AAC -0.11 0.007
mRNA RAB42 GDSC1000 pan-cancer AAC 0.1 0.007
mRNA DCAF16 GDSC1000 pan-cancer AAC -0.098 0.007
mRNA SGK1 GDSC1000 pan-cancer AAC 0.1 0.007
mRNA ATP6V1F GDSC1000 pan-cancer AAC -0.097 0.007
mRNA UBP1 GDSC1000 pan-cancer AAC -0.1 0.007
mRNA AATK GDSC1000 pan-cancer AAC -0.099 0.007
mRNA NPRL2 GDSC1000 pan-cancer AAC -0.1 0.007
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