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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF398 GDSC1000 pan-cancer AAC -0.066 0.06
mRNA ZNF738 GDSC1000 pan-cancer AAC -0.065 0.06
mRNA SH3PXD2B GDSC1000 pan-cancer AAC 0.076 0.06
mRNA RAD54L2 GDSC1000 pan-cancer AAC -0.076 0.06
mRNA LIMD1 GDSC1000 pan-cancer AAC -0.068 0.06
mRNA EPB41L4A GDSC1000 pan-cancer AAC 0.067 0.06
mRNA FAP GDSC1000 pan-cancer AAC 0.07 0.06
mRNA ATG16L2 GDSC1000 pan-cancer AAC -0.073 0.06
mRNA C22orf46 GDSC1000 pan-cancer AAC -0.063 0.06
mRNA JUP GDSC1000 pan-cancer AAC 0.077 0.06
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