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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA YBX2 GDSC1000 pan-cancer AAC -0.067 0.06
mRNA EMD GDSC1000 pan-cancer AAC -0.064 0.06
mRNA HSPB8 GDSC1000 pan-cancer AAC 0.074 0.06
mRNA C1orf116 GDSC1000 pan-cancer AAC 0.081 0.06
mRNA IGFBP3 GDSC1000 pan-cancer AAC 0.073 0.06
mRNA GLB1L2 GDSC1000 pan-cancer AAC -0.073 0.06
mRNA RGS2 GDSC1000 pan-cancer AAC 0.065 0.06
mRNA ARHGDIG GDSC1000 pan-cancer AAC -0.063 0.06
mRNA CEBPA GDSC1000 pan-cancer AAC -0.068 0.06
mRNA MRPL18 GDSC1000 pan-cancer AAC 0.064 0.06
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