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XAV-939

XAV-939

Synonyms

Sources	Names Used
GDSC1000	XAV939
PharmacoGx	XAV-939

External IDs

Database	Identifier
Smiles:	C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey:	KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem:	2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XAV-939

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	OR5AN1	GDSC1000	pan-cancer	AAC	0.061	0.07
mRNA	TXLNA	GDSC1000	pan-cancer	AAC	-0.063	0.07
mRNA	CNPY4	GDSC1000	pan-cancer	AAC	-0.069	0.07
mRNA	GRAMD4	GDSC1000	pan-cancer	AAC	-0.065	0.07
mRNA	CISD3	GDSC1000	pan-cancer	AAC	-0.066	0.07
mRNA	SEC14L4	GDSC1000	pan-cancer	AAC	-0.061	0.07
mRNA	RARRES1	GDSC1000	pan-cancer	AAC	0.066	0.07
mRNA	ICAM5	GDSC1000	pan-cancer	AAC	-0.06	0.07
mRNA	RPL3	GDSC1000	pan-cancer	AAC	-0.066	0.07
mRNA	NGLY1	GDSC1000	pan-cancer	AAC	-0.078	0.07

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