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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA S100A7 GDSC1000 pan-cancer AAC 0.066 0.07
mRNA PHC2 GDSC1000 pan-cancer AAC 0.067 0.07
mRNA DDX27 GDSC1000 pan-cancer AAC -0.061 0.07
mRNA NABP1 GDSC1000 pan-cancer AAC 0.065 0.07
mRNA IGLL5 GDSC1000 pan-cancer AAC -0.068 0.07
mRNA NREP GDSC1000 pan-cancer AAC 0.071 0.07
mRNA C1orf162 GDSC1000 pan-cancer AAC -0.066 0.07
mRNA CARD14 GDSC1000 pan-cancer AAC 0.064 0.07
mRNA INSL3 GDSC1000 pan-cancer AAC 0.06 0.07
mRNA SPEN GDSC1000 pan-cancer AAC -0.066 0.07
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