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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA GATAD2B GDSC1000 pan-cancer AAC -0.069 0.07
mRNA ZNF7 GDSC1000 pan-cancer AAC -0.061 0.07
mRNA ADAM19 GDSC1000 pan-cancer AAC 0.062 0.07
mRNA BUB3 GDSC1000 pan-cancer AAC -0.065 0.07
mRNA GALNTL5 GDSC1000 pan-cancer AAC 0.062 0.07
mRNA C1orf43 GDSC1000 pan-cancer AAC -0.066 0.07
mRNA ZNF578 GDSC1000 pan-cancer AAC -0.061 0.07
mRNA BTNL3 GDSC1000 pan-cancer AAC -0.067 0.07
mRNA KLK10 GDSC1000 pan-cancer AAC 0.074 0.07
mRNA NKX6-1 GDSC1000 pan-cancer AAC -0.066 0.07
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