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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA TTYH2 GDSC1000 pan-cancer AAC -0.068 0.06
mRNA COX7A2L GDSC1000 pan-cancer AAC -0.064 0.06
mRNA C2orf42 GDSC1000 pan-cancer AAC -0.067 0.06
mRNA AGPAT2 GDSC1000 pan-cancer AAC -0.071 0.06
mRNA DEFB114 GDSC1000 pan-cancer AAC 0.062 0.06
mRNA TUBA4A GDSC1000 pan-cancer AAC 0.07 0.06
mRNA UBE2N GDSC1000 pan-cancer AAC -0.067 0.06
mRNA PEPD GDSC1000 pan-cancer AAC -0.065 0.07
mRNA LAT2 GDSC1000 pan-cancer AAC -0.083 0.07
mRNA DLEC1 GDSC1000 pan-cancer AAC 0.062 0.07
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