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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA RNASE7 GDSC1000 pan-cancer AAC 0.071 0.06
mRNA ITGA5 GDSC1000 pan-cancer AAC 0.072 0.06
mRNA DLGAP1 GDSC1000 pan-cancer AAC -0.065 0.06
mRNA FOXD4 GDSC1000 pan-cancer AAC -0.066 0.06
mRNA PRADC1 GDSC1000 pan-cancer AAC -0.066 0.06
mRNA IQGAP3 GDSC1000 pan-cancer AAC -0.066 0.06
mRNA EFNA1 GDSC1000 pan-cancer AAC 0.083 0.06
mRNA ITPK1 GDSC1000 pan-cancer AAC -0.069 0.06
mRNA IL1B GDSC1000 pan-cancer AAC 0.069 0.06
mRNA WDR36 GDSC1000 pan-cancer AAC 0.067 0.06
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