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YK 4-279

YK 4-279

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	YK 4-279
PharmacoGx	YK 4-279

External IDs

Database	Identifier
Smiles:	COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl

Annotated Targets

EWSR1, FLI1, DHX9, ERG, ETV1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to YK 4-279

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRR15L	GDSC1000	pan-cancer	AAC	-0.27	1e-09
mRNA	TFAP4	CTRPv2	pan-cancer	AAC	0.22	1e-09
mRNA	KHDRBS1	CTRPv2	pan-cancer	AAC	0.2	1e-09
mRNA	RHOC	CTRPv2	pan-cancer	AAC	-0.23	2e-09
mRNA	DIMT1	GDSC1000	pan-cancer	AAC	0.22	3e-09
mRNA	RBM10	CTRPv2	pan-cancer	AAC	0.2	3e-09
mRNA	FAM117B	CTRPv2	pan-cancer	AAC	0.2	3e-09
mRNA	YARS2	GDSC1000	pan-cancer	AAC	0.22	4e-09
mRNA	CMTM3	GDSC1000	pan-cancer	AAC	0.22	1e-08
mRNA	PRPF38A	CTRPv2	pan-cancer	AAC	0.2	1e-08

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