RITA

Synonyms

Sources	Names Used
CTRPv2	RITA
PharmacoGx	RITA

External IDs

Database	Identifier
Smiles:	C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Inchikey:	KZENBFUSKMWCJF-UHFFFAOYSA-N
Pubchem:	374536

Annotated Targets

MDM2, TP53

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to RITA

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SULT1A1	CTRPv2	pan-cancer	AAC	0.41	4e-34
mRNA	SULT1A2	CTRPv2	pan-cancer	AAC	0.28	2e-16
mRNA	SULT1A4	CTRPv2	pan-cancer	AAC	0.26	2e-13
mRNA	FAM110D	CTRPv2	pan-cancer	AAC	0.25	4e-13
mRNA	SULT1A3	CTRPv2	pan-cancer	AAC	0.25	2e-12
mRNA	INSR	CTRPv2	pan-cancer	AAC	0.23	2e-09
mRNA	TMEM37	CTRPv2	pan-cancer	AAC	0.22	1e-08
mRNA	KLHDC8B	CTRPv2	pan-cancer	AAC	0.2	2e-08
mRNA	NHLRC4	CTRPv2	pan-cancer	AAC	0.22	3e-08
mRNA	MYO15B	CTRPv2	pan-cancer	AAC	0.21	3e-08

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