5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF85	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	ZNF880	CTRPv2	pan-cancer	AAC	-0.12	0.0007
mRNA	ZNF91	CTRPv2	pan-cancer	AAC	-0.089	0.009
mRNA	ZNHIT1	CTRPv2	pan-cancer	AAC	-0.088	0.01
mRNA	ZSCAN18	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	ZSCAN21	CTRPv2	pan-cancer	AAC	-0.089	0.01
mRNA	ZSCAN25	CTRPv2	pan-cancer	AAC	-0.095	0.006
mRNA	ZSCAN26	CTRPv2	pan-cancer	AAC	-0.081	0.02
mRNA	ZSWIM3	CTRPv2	pan-cancer	AAC	-0.084	0.02
mRNA	ZXDC	CTRPv2	pan-cancer	AAC	0.11	0.002

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