5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TMEM184B	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	PTK2	CTRPv2	pan-cancer	AAC	-0.12	0.003
mRNA	ZNF677	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	CCL15-CCL14	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	PARVA	CTRPv2	pan-cancer	AAC	-0.12	0.003
mRNA	SLC7A1	CTRPv2	pan-cancer	AAC	0.1	0.003
mRNA	LMNB1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	TCERG1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	AC127070.1	CTRPv2	pan-cancer	AAC	-0.1	0.003
mRNA	SPOCK1	CTRPv2	pan-cancer	AAC	-0.11	0.003

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