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Panobinostat

Synonyms

SourcesNames Used
CCLE, FIMMPanobinostat
GRAYLBH589
CTRPv2LBH-589
PharmacoGx Panobinostat

External IDs

DatabaseIdentifier
Smiles: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO
Inchikey: FPOHNWQLNRZRFC-ZHACJKMWSA-N
Pubchem: 6918837

Annotated Targets

HDAC8, HDAC1, HDAC2, HDAC3, HDAC4, HDAC6, HDAC7, HDAC9, HDAC5, HDAC10

FDA Approval Status

Not Approved
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Top molecular features associated with response to Panobinostat


Feature TypeStandardized
Nominal ANOVA
mRNA CYR61 CCLE pan-cancer AAC -0.41 3e-13
mRNA CBX2 CTRPv2 pan-cancer AAC 0.26 1e-12
mRNA MBTD1 CTRPv2 pan-cancer AAC 0.27 2e-12
mRNA MEX3A CTRPv2 pan-cancer AAC 0.28 2e-12
mRNA MYOF CTRPv2 pan-cancer AAC -0.27 3e-12
mRNA GPX8 CCLE pan-cancer AAC -0.41 3e-12
mRNA TMED7-TICAM2 CTRPv2 pan-cancer AAC -0.26 3e-12
mRNA EIF4EBP2 CCLE pan-cancer AAC 0.29 1e-11
mRNA CD109 CTRPv2 pan-cancer AAC -0.25 1e-11
mRNA RMND5A CTRPv2 pan-cancer AAC 0.25 2e-11
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