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Panobinostat

Synonyms

SourcesNames Used
CCLE, FIMMPanobinostat
GRAYLBH589
CTRPv2LBH-589
PharmacoGx Panobinostat

External IDs

DatabaseIdentifier
Smiles: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO
Inchikey: FPOHNWQLNRZRFC-ZHACJKMWSA-N
Pubchem: 6918837

Annotated Targets

HDAC8, HDAC1, HDAC2, HDAC3, HDAC4, HDAC6, HDAC7, HDAC9, HDAC5, HDAC10

FDA Approval Status

Not Approved
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Top molecular features associated with response to Panobinostat


Feature TypeStandardized
Nominal ANOVA
mRNA OSMR CCLE pan-cancer AAC -0.3 8e-09
mRNA CTTNBP2NL CCLE pan-cancer AAC -0.3 6e-08
mRNA CFL2 CCLE pan-cancer AAC -0.29 5e-08
mRNA PXDC1 CCLE pan-cancer AAC -0.29 7e-09
mRNA CNN3 CCLE pan-cancer AAC -0.28 8e-07
mRNA FAM114A1 CCLE pan-cancer AAC -0.28 2e-06
mRNA FHL2 CCLE pan-cancer AAC -0.28 2e-07
mRNA HRH1 CCLE pan-cancer AAC -0.27 1e-09
mRNA NNMT CCLE pan-cancer AAC -0.27 1e-09
mRNA CAV1 CCLE pan-cancer AAC -0.27 3e-08
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