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Panobinostat

Synonyms

SourcesNames Used
CCLE, FIMMPanobinostat
GRAYLBH589
CTRPv2LBH-589
PharmacoGx Panobinostat

External IDs

DatabaseIdentifier
Smiles: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO
Inchikey: FPOHNWQLNRZRFC-ZHACJKMWSA-N
Pubchem: 6918837

Annotated Targets

HDAC8, HDAC1, HDAC2, HDAC3, HDAC4, HDAC6, HDAC7, HDAC9, HDAC5, HDAC10

FDA Approval Status

Not Approved
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Top molecular features associated with response to Panobinostat


Feature TypeStandardized
Nominal ANOVA
mRNA KLHL23 CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA COQ8A CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA PRSS23 CCLE pan-cancer AAC -0.33 5e-11
mRNA ZBED4 CTRPv2 pan-cancer AAC 0.25 6e-11
mRNA ARSJ CCLE pan-cancer AAC -0.31 9e-11
mRNA LARP6 CCLE pan-cancer AAC -0.34 1e-10
mRNA PPIA CCLE pan-cancer AAC 0.26 2e-10
mRNA IFIT1 CCLE pan-cancer AAC -0.27 2e-10
mRNA MYOF CCLE pan-cancer AAC -0.34 2e-10
mRNA FANCF CTRPv2 pan-cancer AAC 0.22 3e-10
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