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MS-275

Synonyms

SourcesNames Used
GDSC1000MS-275
gCSIms275
FIMMEntinostat
CTRPv2entinostat
PharmacoGx MS-275

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
Inchikey: INVTYAOGFAGBOE-UHFFFAOYSA-N
Pubchem: 4261

FDA Approval Status

Not Approved
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Top molecular features associated with response to MS-275


Feature TypeStandardized
Nominal ANOVA
mRNA CNNM1 gCSI pan-cancer AAC -0.17 0.005
mRNA PRPF40A gCSI pan-cancer AAC 0.14 0.005
mRNA MAGEB18 CTRPv2 pan-cancer AAC 0.087 0.005
mRNA HOXC6 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA C9orf24 CTRPv2 pan-cancer AAC 0.089 0.005
mRNA FAM76B CTRPv2 pan-cancer AAC 0.1 0.005
mRNA RORC FIMM pan-cancer AAC 0.35 0.005
mRNA KRTAP10-10 CTRPv2 pan-cancer AAC 0.09 0.005
mRNA CD86 GDSC1000 pan-cancer AAC -0.16 0.005
mRNA RIOK1 CTRPv2 pan-cancer AAC 0.097 0.005
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