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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TOR3A	GDSC1000	pan-cancer	AAC	0.1	0.09
mRNA	PLEKHS1	GDSC1000	pan-cancer	AAC	0.089	0.09
mRNA	DEFB108B	GDSC1000	pan-cancer	AAC	-0.091	0.09
mRNA	TOR1A	GDSC1000	pan-cancer	AAC	0.085	0.09
mRNA	PRSS27	GDSC1000	pan-cancer	AAC	-0.094	0.09
mRNA	UGGT2	GDSC1000	pan-cancer	AAC	0.092	0.09
mRNA	HPS5	GDSC1000	pan-cancer	AAC	0.1	0.09
mRNA	PKHD1	GDSC1000	pan-cancer	AAC	-0.088	0.09
mRNA	CCDC59	GDSC1000	pan-cancer	AAC	-0.092	0.09
mRNA	CLDN1	GDSC1000	pan-cancer	AAC	0.11	0.09

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