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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KIF3C	GDSC1000	pan-cancer	AAC	-0.21	0.002
mRNA	COL4A4	GDSC1000	pan-cancer	AAC	0.17	0.002
mRNA	COL11A2	GDSC1000	pan-cancer	AAC	0.16	0.002
mRNA	SCAF11	GDSC1000	pan-cancer	AAC	0.17	0.002
mRNA	GINS3	GDSC1000	pan-cancer	AAC	0.18	0.002
mRNA	SERPINB11	GDSC1000	pan-cancer	AAC	0.15	0.002
mRNA	AKIP1	GDSC1000	pan-cancer	AAC	-0.17	0.002
mRNA	NUP210	GDSC1000	pan-cancer	AAC	0.25	0.002
mRNA	CFAP74	GDSC1000	pan-cancer	AAC	-0.16	0.002
mRNA	ITM2A	GDSC1000	pan-cancer	AAC	-0.19	0.002

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