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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HNRNPK	GDSC1000	pan-cancer	AAC	0.2	0.0002
mRNA	ARF6	GDSC1000	pan-cancer	AAC	0.21	0.0002
mRNA	TMEM55A	GDSC1000	pan-cancer	AAC	-0.21	0.0003
mRNA	C1GALT1C1	GDSC1000	pan-cancer	AAC	0.2	0.0003
mRNA	ASIP	GDSC1000	pan-cancer	AAC	-0.19	0.0003
mRNA	PPP1R2	GDSC1000	pan-cancer	AAC	0.19	0.0004
mRNA	ANO10	GDSC1000	pan-cancer	AAC	-0.19	0.0004
mRNA	SPG21	GDSC1000	pan-cancer	AAC	-0.18	0.0004
mRNA	HFE	GDSC1000	pan-cancer	AAC	0.21	0.0005
mRNA	C1orf216	GDSC1000	pan-cancer	AAC	-0.18	0.0005

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