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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	THBS1	GDSC1000	pan-cancer	AAC	0.17	0.02
mRNA	TRA2B	GDSC1000	pan-cancer	AAC	0.17	0.003
mRNA	HVCN1	GDSC1000	pan-cancer	AAC	0.18	0.009
mRNA	GINS3	GDSC1000	pan-cancer	AAC	0.18	0.002
mRNA	RHBDL2	GDSC1000	pan-cancer	AAC	0.18	0.003
mRNA	SLC44A1	GDSC1000	pan-cancer	AAC	0.18	0.0006
mRNA	CYR61	GDSC1000	pan-cancer	AAC	0.18	0.03
mRNA	TEP1	GDSC1000	pan-cancer	AAC	0.18	0.003
mRNA	CRYBG3	GDSC1000	pan-cancer	AAC	0.18	0.0008
mRNA	IL17RC	GDSC1000	pan-cancer	AAC	0.18	0.005

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