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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	WNT3A	GDSC1000	pan-cancer	AAC	0.097	0.07
mRNA	C22orf42	GDSC1000	pan-cancer	AAC	-0.09	0.07
mRNA	CLEC3A	GDSC1000	pan-cancer	AAC	0.09	0.07
mRNA	CMC1	GDSC1000	pan-cancer	AAC	-0.1	0.07
mRNA	OR7G2	GDSC1000	pan-cancer	AAC	-0.09	0.07
mRNA	NRM	GDSC1000	pan-cancer	AAC	0.096	0.07
mRNA	USP10	GDSC1000	pan-cancer	AAC	-0.1	0.07
mRNA	SNRNP27	GDSC1000	pan-cancer	AAC	-0.093	0.07
mRNA	CEP104	GDSC1000	pan-cancer	AAC	-0.093	0.07
mRNA	TMEM68	GDSC1000	pan-cancer	AAC	-0.09	0.08

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