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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ADGRF1	GDSC1000	pan-cancer	AAC	0.13	0.02
mRNA	TRAM1	GDSC1000	pan-cancer	AAC	0.14	0.02
mRNA	DCAF6	GDSC1000	pan-cancer	AAC	0.13	0.02
mRNA	TTR	GDSC1000	pan-cancer	AAC	-0.13	0.02
mRNA	BMP3	GDSC1000	pan-cancer	AAC	0.12	0.02
mRNA	ARID5B	GDSC1000	pan-cancer	AAC	0.13	0.02
mRNA	ETS2	GDSC1000	pan-cancer	AAC	-0.12	0.02
mRNA	MSMB	GDSC1000	pan-cancer	AAC	0.26	0.02
mRNA	KLHL4	GDSC1000	pan-cancer	AAC	-0.12	0.02
mRNA	SEMA4C	GDSC1000	pan-cancer	AAC	-0.13	0.02

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