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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	VPREB3	GDSC1000	pan-cancer	AAC	0.15	0.006
mRNA	ZSCAN31	GDSC1000	pan-cancer	AAC	0.15	0.006
mRNA	NTPCR	GDSC1000	pan-cancer	AAC	-0.14	0.007
mRNA	EVX1	GDSC1000	pan-cancer	AAC	-0.14	0.007
mRNA	RCSD1	GDSC1000	pan-cancer	AAC	0.22	0.007
mRNA	TSHR	GDSC1000	pan-cancer	AAC	0.14	0.007
mRNA	HS3ST2	GDSC1000	pan-cancer	AAC	-0.14	0.007
mRNA	ATP11B	GDSC1000	pan-cancer	AAC	0.16	0.007
mRNA	L1TD1	GDSC1000	pan-cancer	AAC	-0.15	0.007
mRNA	SENP5	GDSC1000	pan-cancer	AAC	0.14	0.007

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