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A-443654

A-443654

Synonyms

Sources	Names Used
GDSC1000	A-443654
PharmacoGx	A-443654

External IDs

Database	Identifier
Smiles:	CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CNC5=CC=CC=C54)N
Inchikey:	YWTBGJGMTBHQTM-IBGZPJMESA-N
Pubchem:	10172943

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to A-443654

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FAM111A	GDSC1000	pan-cancer	AAC	0.19	0.002
mRNA	IRF3	GDSC1000	pan-cancer	AAC	0.2	0.0008
mRNA	GPX8	GDSC1000	pan-cancer	AAC	0.2	0.02
mRNA	HNRNPK	GDSC1000	pan-cancer	AAC	0.2	0.0002
mRNA	C1GALT1C1	GDSC1000	pan-cancer	AAC	0.2	0.0003
mRNA	EFEMP1	GDSC1000	pan-cancer	AAC	0.2	0.002
mRNA	IKZF1	GDSC1000	pan-cancer	AAC	0.21	0.09
mRNA	ICAM2	GDSC1000	pan-cancer	AAC	0.21	0.02
mRNA	HFE	GDSC1000	pan-cancer	AAC	0.21	0.0005
mRNA	SEC62	GDSC1000	pan-cancer	AAC	0.21	2e-05

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