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Pyrimethamine

Synonyms

SourcesNames Used
GDSC1000Pyrimethamine
PharmacoGx Pyrimethamine

External IDs

DatabaseIdentifier
Smiles: CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
Inchikey: WKSAUQYGYAYLPV-UHFFFAOYSA-N
Pubchem: 4993

Annotated Targets

DHFR, SLC47A1

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Pyrimethamine


Feature TypeStandardized
Nominal ANOVA
mRNA RAD52 GDSC1000 pan-cancer AAC 0.2 0.0001
mRNA CABP2 GDSC1000 pan-cancer AAC -0.2 0.0001
mRNA DDIT4 GDSC1000 pan-cancer AAC 0.2 0.0001
mRNA BTF3L4 GDSC1000 pan-cancer AAC 0.21 0.0002
mRNA FBXL13 GDSC1000 pan-cancer AAC 0.19 0.0002
mRNA APLP2 GDSC1000 pan-cancer AAC -0.21 0.0002
mRNA MAGEC3 GDSC1000 pan-cancer AAC -0.21 0.0002
mRNA P4HA1 GDSC1000 pan-cancer AAC 0.21 0.0002
mRNA YARS GDSC1000 pan-cancer AAC 0.21 0.0002
mRNA USF2 GDSC1000 pan-cancer AAC 0.21 0.0003
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