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Pyrimethamine

Synonyms

SourcesNames Used
GDSC1000Pyrimethamine
PharmacoGx Pyrimethamine

External IDs

DatabaseIdentifier
Smiles: CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
Inchikey: WKSAUQYGYAYLPV-UHFFFAOYSA-N
Pubchem: 4993

Annotated Targets

DHFR, SLC47A1

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Pyrimethamine


Feature TypeStandardized
Nominal ANOVA
mRNA CXCR6 GDSC1000 pan-cancer AAC -0.19 0.0004
mRNA KEL GDSC1000 pan-cancer AAC 0.18 0.0004
mRNA RNF167 GDSC1000 pan-cancer AAC 0.18 0.0004
mRNA LRP6 GDSC1000 pan-cancer AAC 0.23 0.0004
mRNA GARS GDSC1000 pan-cancer AAC 0.18 0.0005
mRNA ATXN2L GDSC1000 pan-cancer AAC 0.2 0.0005
mRNA CLIC4 GDSC1000 pan-cancer AAC 0.2 0.0005
mRNA PPIL4 GDSC1000 pan-cancer AAC 0.18 0.0006
mRNA BANK1 GDSC1000 pan-cancer AAC -0.19 0.0006
mRNA C11orf94 GDSC1000 pan-cancer AAC -0.18 0.0006
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