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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA HRK CTRPv2 pan-cancer AAC -0.094 0.008
mRNA ACTRT2 CTRPv2 pan-cancer AAC -0.092 0.008
mRNA KCNT1 CTRPv2 pan-cancer AAC 0.098 0.008
mRNA MRPL49 GDSC1000 pan-cancer AAC -0.091 0.008
mRNA ADSL CTRPv2 pan-cancer AAC -0.1 0.008
mRNA ARSB GDSC1000 pan-cancer AAC 0.09 0.008
mRNA CHST12 GDSC1000 pan-cancer AAC 0.088 0.008
mRNA FANCI CTRPv2 pan-cancer AAC -0.099 0.008
mRNA CD3EAP GDSC1000 pan-cancer AAC 0.084 0.008
mRNA FBRSL1 GDSC1000 pan-cancer AAC 0.089 0.008
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