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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA PPP1R27 GDSC1000 pan-cancer AAC 0.23 7e-13
mRNA PRDM1 CTRPv2 pan-cancer AAC 0.25 1e-11
mRNA WNT10B GDSC1000 pan-cancer AAC 0.2 2e-10
mRNA ZNF740 CTRPv2 pan-cancer AAC 0.22 6e-10
mRNA IGF1R GDSC1000 pan-cancer AAC 0.21 6e-10
mRNA CD79A CTRPv2 pan-cancer AAC -0.24 2e-09
mRNA IL6R CTRPv2 pan-cancer AAC 0.22 2e-09
mRNA SPCS1 CTRPv2 pan-cancer AAC 0.21 3e-09
mRNA RP4-583P15.14 CTRPv2 pan-cancer AAC 0.22 3e-09
mRNA SELPLG CTRPv2 pan-cancer AAC 0.23 6e-09
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